West Coast Sarcoma Conference 2024: Session 1 – Benign Conditions with Oncologic Strategies
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Chair
Dr. Christine Simmons
Speakers
Dr. Jonathan Noujaim
Dr. Theirry Alcindor
Dr. Torsten Nielsen
Dr. Shannon Puloski
Dr. Elliott Weiss
Studies/trials discussed:
- WNT signaling pathway
- An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG)
- Sorafenib for Advanced and Refractory Desmoid Tumors
- ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts
- Molecular pathogenesis of desmoid tumor and the role of γ-secretase inhibition
- Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors
- Tumor Volume and T2 Hyperintensity Changes from DeFi: A Phase 3, Randomized, Controlled Trial of Nirogacestat in Patients With Desmoid Tumors
- Molecular Cytogenic mapping of recurrent chromosomal breakpoints in tenosynovial giant cell tumors
- Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor
- Complete response to imatinib in relapsing pigmented vilonodular synovitis/tenosynovial giant cell tumor
- Massively parallel sequencing of tenosynovial giant cell tumors reveal novel CSF1 fusion transcripts and novel somatic CBL mutations
- Detection of CSF1 rearrangements deleting the 3 UTR in tenosynovial giant cell tumors
- Neoplasiaassociated chromosome Translocations Resulting in Gene Truncation
- Neoplastic synovial lining cells that coespress podoplanin and CD90 overproduce CSF-1, driving tenosynovial giant cell tumor
- Interactions in CSF1-driven Tenosynovial Giant cell Tumors
- Distinct In vivo roles of colony stimulating factor-1 Isoforms in Renal inflammation
- Interactions in CSF1-Driven Tenosynovial Giant Cell Tumors
- Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations
- Detection of CSF1 Rearrangements deleting the 3 UTR in tenosynovial giant cell tumors
- Surgical management of 144 diffuse-type TGCT patients in a single institution: A 20year cohort study
- Surgical outcomes of patients with diffuse type tenosynovial giant cell tumors: an international, reytrospective, cohort study.
- A comparison of open and arthroscopic surgery for treatment of diffuse pigmented villondular synovitis of the knee
- Giant cell tumor of tendon sheath: open surgery or arthroscopic synovectomy? A systematic review of the literature
- Arthroscopic versus open management of diffuse type tenosynovial giant cell tumor of the knee: A meta analysis of retrospective cohort studies.
- Open versus arthroscopc surgery for diffuse tenosynovial giant cell tumors of the knee: a systematic review.
