CHICAGO HIGHLIGHTS 2024 – GI ROUNDTABLE DISCUSSION: GIANT

Icon Chair Speaker

Chair

Dr. Scott Berry

Icon Chair Speaker

Panelists

Dr. Sharlene Gill
Dr. Florian Lordick

Studies/trials discussed:

  • The GIANT trial (ECOG-ACRIN EA2186) methods paper: A randomized phase II study of gemcitabine and nab-paclitaxel compared with 5-fluorouracil, leucovorin, and liposomal irinotecan in older patients with treatment-naïve metastatic pancreatic cancer defining a new treatment option for older vulnerable patients
  • ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286)