BEST OF HEMATOLOGY 2024: Amyloidosis – Dr. Donna Reece

Icon Chair Speaker

Chair

Dr. Martina Trinkaus
Dr. Matthew Seftel

Icon Panelists

Panelist

Dr. Donna Reece

Studies/trials discussed:

  • Systemic amyloidosis from A (AA) to T (ATTR): a review
  • Systemic immunoglobulin light chain amyloidosis
  • Characterization of Systemic Amyloid Deposits by Mass Spectrometry
  • Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements
  • Limited Utility of Mayo 2012 Cardiac Staging System for Risk Stratification of Patients with Advanced Cardiac AL Amyloidosis Analysis of a Uniformly Treated Cohort of 1275 Patients
  • Clarification on the definition of complete haematologic response in light-chain (AL) amyloidosis
  • Identifying Early Suboptimal Hematological Response in Patients with AL Amyloidosis Treated with Bortezomib-Based Chemotherapy
  • Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis
  • Subcutaneous Daratumumab with Bortezomib, Cyclophosphamide, and Dexamethasone in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis: 18-Month Analysis of the Phase 3 ANDROMEDA Study
  • AL amyloidosis: untangling new therapies
  • Role of autologous haematopoietic cell transplantation in the treatment of systemic light chain amyloidosis in the era of anti-CD38 monoclonal antibodies
  • Safety, tolerability, and response rates of daratumumab in relapsed AL amyloidosis: results of a phase 2 study
  • Phase 2 Study of Daratumumab (DARA) Plus Bortezomib, Cyclophosphamide, and Dexamethasone (D-VCd) in a Diverse Patient Population with Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis: Aquarius
  • Venetoclax induces deep hematologic remissions in t(11;14) relapsed/refractory AL amyloidosis
  • Outcomes of Venetoclax-Based Therapy in Patients with Daratumumab-Refractory t(11;14) Positive Light Chain Amyloidosis
  • Outcomes of t(11;14) light chain (AL) amyloidosis after autologous stem cell transplantation: benchmark for new therapies
  • Efficacy and Safety of Belantamab Mafodotin Monotherapy in Patients with Relapsed or Refractory Light Chain Amyloidosis: A Phase 2 Study By the European Myeloma Network
  • Pooled Analysis of Safety from Birtamimab Phase 1-3 Studies in Patients with Light Chain (AL) Amyloidosis
  • Updated OS of patients with AL amyloidosis after CAEL-101.
  • Safety and Tolerability of Cael-101, an Anti-Amyloid Monoclonal Antibody, Combined with Anti-Plasma Cell Dyscrasia Therapy in Patients with Light-Chain Amyloidosis: 24-Month Results of a Phase 2 Study
  • Cael-101 Enhances the Clearance of Light Chain Fibrils and Intermediate Aggregates By Phagocytosis
  • Safety and Efficacy of Teclistamab in Patients with Relapsed or Refractory AL Amyloidosis: A Retrospective Case Series
  • Feasibility of a Novel Academic Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) (HBI0101) for the Treatment of Relapsed and Refractory AL Amyloidosis
  • Treatment of Al Amyloidosis in Canada