BEST OF ONCOLOGY WEST 2024: Astellas Lunch Symposium: Biomarker Directed Therapies in Gastric/Gastroesophageal Cancers and Review of the Latest Evidence – Dr. Sharlene Gill

Icon Chair Speaker

Chair

Dr. Sharlene Gill
Dr. Daniel Heng

Icon Panelists

Panelist

Dr. Sharlene Gill

This program has been made possible through unrestricted support from Astellas

Studies/trials discussed:

  • First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
  • Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma
  • Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial
  • Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study
  • Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial
  • Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial
  • Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial